PLTMax®

PLTMax^®

Quality. Experience. Growth.

Over 15 Years of Successful Clinical Use

PLTMax^® is our original, first-generation human platelet lysate developed as an animal serum-free, cell culture supplement and was the first commercially available human platelet lysate.

This product is animal serum-free, however, heparin is added in the manufacturing process of PLTMax^® to minimize coagulation. Even with the addition of heparin, clots can spontaneously develop over time. Avoiding long term storage at 4°C can help with reducing the number and size of clots. Since some cell culture media contain high levels of mediators of coagulation like Ca₂+ and Mg₂+, the addition of heparin is also required when preparing complete media supplemented with PLTMax^®.

For PLTMax^® production, we use pharmaceutical grade heparin for injection. This heparin is purified and refined from swine according to cGMP methods and is one of the most widely used drugs in humans.

PLTMax^® has been a critical ingredient in Phase I, Phase II, and Phase III trials worldwide. It has been used to grow cells for thousands of patients. PLTMax^® has a Master File with the FDA to accelerate your application.

Available in both clinical and research grades in 27mL, 100mL, 500mL, and 1000mL bottles.

Benefits of PLTMax^®

Adipose-derived MSCs reduced doubling times

Increased cell growth kinetics (reduced cell doubling time)
Contains growth factors and proteins that maximize cell growth

Enhances genetic stability in MSC cultures
Provides an optimal environment for cell culture and drug discovery
Manufactured to reduce lot-to-lot variation

Adipose-derived MSCs maintain capacity to undergo adipogenesis after growth with PLTMax^®

Human umbilical vein endothelial cells

Not just for MSCs, but also Endothelial cells, T cells, NK cells, tumor cells, iPSCs, and more!
Great for generating cells in large scale bioreactors
Master File with the FDA

Reduced supplementation (5% or less supplementation with PLTMax^® compared to 10% or more FBS and Human AB Serum)
More cost-effective alternative to serum free media supplements

Adipose-derived MSCs increased cell growth

Quality Products to Fit Your Needs

All our products are manufactured under cGMP conditions. We do release testing on all manufactured lots and provide a CoA/CoO for each lot. Some of our release testing includes: pH, osmolality, total protein, mycoplasma, sterility, endotoxin, and a proprietary cell growth assay. We also test a panel of growth factors on all lots for internal information only. Mill Creek is ISO 9001:2015 certified.